Their study showed that the adeno-associated virus 9 (AAV9)-packaged cardiac bridging integrator 1 (cBIN1) gene therapy increased the amount of blood the heart can pump and dramatically improved ...

To try and increase cBIN1 levels in cases of heart failure, the scientists turned to a harmless virus commonly used in gene therapy to deliver an extra copy of the cBIN1 gene to heart cells.

At the University of Utah, scientists used a new gene therapy that was shown to reverse ... have low levels of cardiac bridging integrator 1 (cBIN1), a critical heart protein.

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

TUESDAY, Dec. 10, 2024 (HealthDay News) -- Failing hearts nearly returned to full function in laboratory pigs after they received an experimental gene therapy. New research shows the gene therapy didn ...

Previous attempted therapies for heart failure have shown improvements to heart function on the order of 5-10%. cBIN1 gene therapy improved function by 30%. "It's night and day," Shaw adds.

To try and increase cBIN1 levels in cases of heart failure, the scientists turned to a harmless virus commonly used in gene therapy to deliver an extra copy of the cBIN1 gene to heart cells. They ...

To try and increase cBIN1 levels in cases of heart failure, the scientists turned to a harmless virus commonly used in gene therapy to deliver an extra copy of the cBIN1 gene to heart cells. They ...