In the USA, children with sickle cell disease increasingly survive into adulthood, leading to an expanding population of ...

Advances in genetic cell modifications are performed routinely in research laboratories, but clinical translation requires ...

In 2021, alcohol-related liver cirrhosis accounted for about a quarter of the 46·4 million disability-adjusted life-years (DALYs) lost from liver disease globally, making alcohol a leading cause of ...

Margareth Dalcolmo has spent decades treating and researching respiratory infectious diseases, most notably tuberculosis. Yet ...

Sudden cardiac arrest and death occur among competitive and recreational athletes across the entire spectrum of age, sex, and ...

Despite substantial scientific advances, diagnosis and prognosis after paediatric traumatic brain injury (TBI) remains ...

In 1842, Friedrich Engels walked the streets of Manchester in the UK, noting its crowded tenements and sunless, smoke-filled ...

Armed conflict is increasing throughout the world and disproportionately affects the lives of women and girls. In 2023, an ...

The SELECTION study1 showed that the JAK 1 inhibitor filgotinib is safe and efficacious in ulcerative colitis. Based on positive results of the phase 2 FITZROY study2 in Crohn's disease, it was ...

It has been four decades since the world's deadliest industrial accident, but the impacts are still being felt today. Dinesh ...

This Series on Cancer Care in the South Asian Association for Regional Cooperation (SAARC) countries comprises four papers and a Reportage in The Lancet Oncology. The first two papers focus on cancer ...

The past 10 years have seen an expansion in treatment possibilities for people with haemophilia, driven by the need for better protection against bleeding episodes, more efficient prevention of joint ...