While landing at Ronald Reagan Washington National Airport in Washington, D.C., on Wednesday shortly before 9 p.m., American Airlines Flight 5342 collided with an Army Black Hawk helicopter and crashed into the icy Potomac River.

The last major collision of a commercial U.S. airline dates back to 2009, when a Colgan Air incident left 50 dead near Buffalo, New York. Federal regulators tightened safety requirements following the crash, including bolstering aircraft carrier inspection requirements and pilot training hours.

A regional jet carrying 64 people collided with an Army Black Hawk helicopter. Reagan National Airport grounded all flights.

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American Airlines said the jet had 60 passengers and four crew members, while the Pentagon confirmed that three soldiers were aboard the helicopter. There was no immediate word on fatalities.

An Army Black Hawk helicopter collided with a regional jet near Ronald Reagan Washington National Airport on Wednesday evening, U.S. officials confirmed to ABC News.

An American Airlines flight crashed into military Black Hawk helicopter late Wednesday night near Reagan National Airport. Here are the most recent fatal incidents prior to the crash

Authorities say American Airlines flight 5342 from Wichita, Kansas, was preparing to land before it "collided in midair" with an Army helicopter.