Denali Therapeutics Inc. DNLI announced that the FDA has granted Breakthrough Therapy Designation to its pipeline candidate, ...

DNL343 and fosigotifator are made to activate the ISR pathway protein eIF2B, but both failed to slow ALS progression in the HEALEY trial.

Fast-growing wildfires raging in Los Angeles killed at least two people on Wednesday, destroying hundreds of buildings, scorching hillsides and prompting officials to order some 70,000 people to ...