As the Lions and Bills prepare to play each other in a Week 15 game Sunday, maybe this is the year for one of them.

DJ Reader injured his shoulder in the Detroit Lions' Thanksgiving win over the Chicago Bears but expects to play Sunday vs.

Experts point to Detroit’s dynamic offense and a Bills defense that has struggled recently as key reasons for the Lions’ edge ...

At the time of publication, the cheapest available tickets for the Detroit Lions vs. the Buffalo Bills are $408.

Perhaps it's the price of being among the NFL's elite, or maybe it's the high-profile matchup scheduled this weekend, but ...

The Buffalo Bills will face off against the Detroit Lions in Week 15 of the NFL season on Sunday. This prediction includes ...

You can listen on SiriusXM satellite radio on channel 382 (Bills feed) and channel 227 (Lions feed), and on traditional radio ...

BUFFALO, N.Y. (WIVB) — The Bills will travel to Detroit to take on the Lions in one of the NFL’s most anticipated games all ...

In what is arguably the most highly-anticipated matchup of the Week 15 slate, the Buffalo Bills will travel to Ford Field on ...

The Detroit Lions and Buffalo Bills will face off in a potential Super Bowl preview in Week 15. Will the Lions extend their ...

NFL Week 15 odds, picks, predictions, TV channel, streaming information for Sunday football game between Buffalo Bills and ...

Bills linebacker Matt Milano and defensive tackle DeWayne Carter returned from injured reserve in back-to-back weeks, but ...