San Francisco 49ers star Christian McCaffrey could "potentially" be lost for the season with a knee injury, head coach Kyle Shanahan said Sunday night.

In a heart-stopping moment that left San Francisco 49ers fans holding their breath, Christian McCaffrey's injury scare during ...

Mackenzie Salmon shares the very different weekends between Bills' Josh Allen and 49ers' Christian McCaffrey. Posted: ...

A Monday morning recap of the fantasy football relevant injuries from Week 13 of the NFL season by our Injury Expert Adam ...

Injuries and missed opportunities have defined the San Francisco 49ers' 2024 season. Can they overcome setbacks and make a ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

The San Francisco 49ers clearly struggled to adapt to the weather in Buffalo on Sunday night, and it showed, as the Bills ...

Christian McCaffrey ’s challenging 2024 NFL season took a devastating turn on Sunday when the San Francisco 49ers ’ star ...

San Francisco coach Kyle Shanahan told reporters postgame that their star running back had injured the posterior cruciate ...

San Francisco 49ers quarterback Brock Purdy feels sorry for the brutal injury suffered by Christian McCaffrey.

Trevor Lawrence, Christian McCaffrey and Taysom Hill were among key players injured in Week 13 of the NFL season.

Christian McCaffrey’s injury threatens to sideline the 49ers’ star running back for the rest of the season. The team’s ...